Büchi Glas Uster AG
- Glass Pharma Reactor
Buchi is a leading manufacturer of glass pharma reactors. The design of our reactors fulfils the requests of the authorities (pressure equipment directives and Ex proof equipment ) and of the pharma industry regarding:
- Performance
- suitability for use in cGMP environment
- validation
- compact design
- low temperature or cryogenic applications
and many other factors.
Glass pharma reactors are often used for small scale production of fine chemicals and pharmaceuticals (API’s).
The performance of such reactors depends on several factors, see also (link zu landing page: Büchi Glass - Chemical Reactor Systems
Buchi Glass Pharma reactors are built with a glass lined carbon steel bottom section for better temperature control. The glass section in the upper part or the glass cover allows the chemist to observe the ongoing reaction. The distillation overhead in borosilicate glass with PTFE gaskets is mainly used for (vacuum) distillation. The use of glass lined steel with Borosilicate glass allows processing of a wide range of different substances. The high vacuum (or low leakage rate) of the complete reaction system is crucial for the purity of the final product. This as well as safe chemical processing in glass process equipment we can guarantee by the use of «büchiflex» components of our modular glass components system.
The standard configuration of Buchi Glass Pharma Reactors allow to perform a variety of processes like:
- Distillation, Reflux, Rectification
- Azeotropic distillation (phase separation)
- Evaporation to desired consistency
- Multicomponent reactions
- Gas dispersion into liquid phase
- Extraction/phase separation in reactor
- Crystallization
- Cryogenic / low temperature reaction
Since used for multiple processes and different products, fast and efficient cleaning of such reactors systems is very important. This issue must be respected already in the planning stage by the choice of used materials in such units, as well as in the design of the complete unit to shorten the down time during product changes.
For optional pharma reactor accessories like : pH control, automation, different glass setup, different stirrers, please refer to the section reactor options.
Additional accessories to our pharma reactors are filters, scrubber, glass reactors or mixing vessel, please refer to the relevant section in glassequipment.
Glass Reactor Systems
including:
«miniPilot»
«chemReactor»
Glass process equipment
Engineering
Filters
Glass Reactor
Scrubber
Components
Services
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